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Heart Failure's Global Economic Toll Exceeds $284 Billion, New Study Finds
Added: 7 months ago Source:  Radcliffe Cardiology
The global economic burden of heart failure (HF) reached an estimated $284.17 billion in 2021, highlighting a substantial and growing financial strain on healthcare systems and societies worldwide. A new systematic review reveals that indirect costs, such as productivity loss, now account for over half of this total, signalling a significant shift in the economic impact of the condition… View more

Guidelines & Statements

Heart Failure
Study Finds Multimorbidity Dramatically Increases Mortality Risk in Heart Failure Patients with Mildly Reduced and Preserved Ejection Fraction
Added: 1 year ago Source:  Radcliffe CVRM
A recent study published in Circulation: Heart Failure1 has found that multimorbidity, the presence of two or more chronic health conditions, substantially increases the risk of mortality in patients with heart failure who have mildly reduced (HFmrEF) or preserved ejection fraction (HFpEF).The study analyzed data from two major heart failure trials: TOPCAT-Americas (Treatment of Preserved Cardiac… View more

Prevention & Chronic Conditions

Heart Failure
Clinical Frailty Scale Predicts Mortality in Heart Failure
Added: 3 months ago Source:  Radcliffe Cardiology
Frailty is a common and significant factor associated with adverse outcomes in patients with heart failure, but the prognostic utility of simple assessment tools in contemporary practice remains an area of investigation. A new study using data from a large Japanese registry has found that the Clinical Frailty Scale (CFS) effectively captures both physical and cognitive decline and is an… View more

Prevention & Chronic Conditions

Demographic
PANDA II: In-hospital Influenza Vaccination Reduces Mortality and Readmission in Acute Heart Failure
Added: 7 months ago Source:  Radcliffe Cardiology
For patients hospitalised with acute heart failure, receiving an influenza vaccination prior to discharge can significantly lower the risk of all-cause mortality and subsequent hospital readmission over the following year. These findings come from the PANDA II trial, a large cluster-randomised study conducted in China.¹PANDA II was a pragmatic, multiregional, parallel-group, cluster-randomised,… View more

Heart Failure
Early SGLT2i/MRA Use Benefits Suspected HF Patients
Added: 1 month ago Source:  Cardiac Failure Review Journal
Delays in diagnosis and treatment for patients with suspected heart failure (HF) in the community can lead to preventable hospitalisations and deaths. A new modelling study by Dr Kieran Docherty and colleagues suggests that early initiation of disease-modifying therapies in select patients at the time of an elevated natriuretic peptide test could significantly reduce these adverse outcomes… View more

Intervention

Heart Failure
LBBP Superior to BiVP for HF Outcomes in HeartSync-LBBP
Added: 3 weeks ago Source:  Arrhythmia and Electrophysiology Review
For patients with heart failure (HF) and left bundle-branch block (LBBB), left bundle-branch pacing (LBBP) has been proposed as an alternative to the standard biventricular pacing (BiVP).¹ A new randomised trial, HeartSync-LBBP, has found that LBBP leads to superior long-term clinical outcomes compared with BiVP in this patient population.²MethodologyThe HeartSync-LBBP trial was a multicentre,… View more

Electrophysiology & Arrhythmia

Heart Failure
Delayed ATTR-CM Diagnosis Common in HF Patients
Added: 1 month ago Source:  Radcliffe Cardiology
A new study has revealed significant delays in the diagnosis of transthyretin amyloid cardiomyopathy (ATTR-CM) following an initial diagnosis of heart failure (HF), with the median time to diagnosis exceeding one year.¹ Timely identification of ATTR-CM is critical to reduce morbidity and mortality, as effective treatments are available.²MethodologyThis retrospective cohort study analysed data… View more

Heart Failure
Vericiguat May Reduce Total Worsening HF Events
Added: 3 months ago Source:  Radcliffe Cardiology
An exploratory analysis of the VICTOR trial suggests that in compensated patients with heart failure and reduced ejection fraction (HFrEF), vericiguat may reduce the overall burden of worsening heart failure (HF) when outpatient events are included alongside hospitalisations.¹Vericiguat is an oral soluble guanylate cyclase stimulator that enhances the cyclic guanosine monophosphate pathway,… View more

Prevention & Chronic Conditions

Heart Failure
OPTION-STEMI: Staged Revascularisation for STEMI with HF
Added: 2 weeks ago Source:  Cardiac Failure Review
The optimal timing for complete revascularisation in patients with ST-segment elevation myocardial infarction (STEMI) and multi-vessel disease who also present with heart failure is a key clinical question. A pre-specified subgroup analysis of the OPTION-STEMI trial suggests that a staged approach may be preferable to immediate complete revascularisation in this high-risk patient group… View more

Intervention

MI/ACS
Heart Rate Lowering Benefits are Context-Dependent, Meta-Analysis Finds
Added: 9 months ago Source:  Radcliffe Cardiology
AUTHOR: Jennifer ThomasThe long-standing debate over the benefits of heart rate (HR)-lowering drug treatment, particularly in patients with hypertension, has been addressed in a new large-scale meta-analysis. The findings, published in the European Heart Journal, suggest that the advantages of reducing HR are highly dependent on the patient's underlying clinical condition, with significant… View more

MI/ACS

Prevention & Chronic Conditions