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Added:
1 week ago
Source:
CFR Journal
Consumer wearable devices may offer a scalable method for the daily monitoring of heart failure (HF) symptoms and predicting exacerbations. A new study has detailed how a deep learning model using Apple Watch data can estimate cardiopulmonary fitness and provide early risk discrimination for unplanned healthcare events in patients with HF.¹MethodologyThe Ted Rogers Understanding Exacerbations of…
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Added:
1 month ago
Source:
Radcliffe Cardiology
Transthyretin amyloid cardiomyopathy (ATTR-CM) is a progressive disease associated with a significant burden of recurrent cardiovascular (CV) events. A new post hoc analysis of the ATTRibute-CM trial suggests that acoramidis, an oral transthyretin (TTR) stabiliser, significantly reduces the cumulative burden of these outcomes.¹MethodologyThis exploratory analysis used data from the phase 3,…
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Added:
8 months ago
Source:
Radcliffe Cardiology
A new meta-analysis suggests that the more time an individual's ambulatory blood pressure (ABP) is within the target range proposed by the 2024 European Society of Cardiology (ESC) guidelines, the lower their risk of mortality and cardiovascular events.¹ The findings also highlight that office blood pressure measurements frequently misclassify patients with regard to their actual blood pressure…
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Added:
6 months ago
Source:
Transcatheter Academy
The long-term durability of complete revascularization in older patients with myocardial infarction (MI) and multivessel disease has been a subject of recent debate. New 3-year follow-up data from the Functional Assessment in Elderly MI Patients With Multivessel Disease (FIRE) trial show that the clinical benefits of a physiology-guided complete revascularization strategy are sustained over time…
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Added:
3 weeks ago
Source:
Transcatheter Academy
A new study suggests that for elderly patients with atrial functional mitral regurgitation (AFMR), transcatheter edge-to-edge repair (TEER) is associated with a lower risk of mortality and heart failure hospitalisation compared with conventional medical therapy. The findings come from a propensity score-based comparison of two large Japanese registries, OCEAN-Mitral and REVEAL-AFMR…
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Added:
6 months ago
Source:
Radcliffe Cardiology
AUTHOR: Yazmin SadikNew findings from the DIGIT-HF trial indicate that adding low-dose digitoxin to guideline-directed medical therapy (GDMT) can reduce the risk of hospitalisation and all-cause mortality in patients with symptomatic heart failure with reduced ejection fraction (HFrEF).¹The results were presented at the European Society of Cardiology (ESC) Congress 2025 and simultaneously…
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Added:
8 months ago
Source:
Radcliffe Cardiology
A large-scale, nationwide study from South Korea suggests that vaccination with the live zoster vaccine is associated with a significantly lower risk of various cardiovascular (CV) events in adults aged 50 and older. The findings indicate a protective association that persists for up to 8 years post-vaccination.¹This population-based cohort study analysed data from over 2.2 million individuals…
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Added:
5 months ago
Source:
Radcliffe Cardiology
Observational studies have long suggested that women who experience hypertensive disorders of pregnancy (HDP) face a greater risk of cardiovascular disease (CVD) later in life. A new genetic epidemiological study has explored whether this association is causal, using Mendelian randomization (MR) to investigate the genetic underpinnings of this risk. The findings suggest a genetic predisposition…
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Added:
1 month ago
Source:
Radcliffe Cardiology
Therapies for transthyretin amyloidosis with cardiomyopathy (ATTR-CM), including transthyretin (TTR) stabilisers and silencers, have demonstrated a mortality benefit in randomised trials. However, the timing of this benefit has been a subject of debate. A new analysis of three major outcomes trials has evaluated this time course, revealing a consistent pattern across different treatments…
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Added:
11 months ago
Source:
Radcliffe Cardiology
AUTHOR: Sean DelaneyIn the landmark FAIR-HF2 randomized clinical trial (NCT03036462)1, intravenous (IV) ferric carboxymaltose did not significantly reduce heart failure (HF) hospitalizations or cardiovascular deaths in patients with heart failure and iron deficiency, despite improving patient-reported quality of life outcomes. Results were presented at ACC.252 and concurrently published in JAMA3…
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