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Added:
4 months ago
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Radcliffe Cardiology
Communicating long-term cardiovascular disease (CVD) risk to younger adults can be challenging, but new research offers a tool to frame risk relative to an individual's peers. Investigators have developed population-based, age- and sex-specific percentiles for 30-year risk of CVD, atherosclerotic cardiovascular disease (ASCVD), and heart failure (HF) using the PREVENT (Predicting Risk of CVD…
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Added:
1 year ago
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Radcliffe Cardiology
AUTHOR: Jordan Rance; Special Editor: Greg GuilloryA new analysis sheds light on the timing of protection offered by SGLT2 inhibitors. Researchers conducted a cross-trial analysis using individual participant data from four large-scale randomized clinical trials: CANVAS (type 2 diabetes with high atherosclerotic risk, NCT01032629), CREDENCE (diabetic kidney disease, NCT02065791), DAPA-HF (heart…
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Added:
9 months ago
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ESC Congress 2025 Scientific Programme
Ten hot line sessions have been announced for ESC Congress 2025.The congress is set to take place from the 29th August to 1st September at IFEMA - Fiera de Madrid.Access the full programme here.Hot Line 1Friday 29th August, 11:00am – 12:00pm (CEST)POTCAST – a Randomized Controlled Trial of Arrhythmia prevention using targeted plasma potassium levels in ICD Patients – Presented by Christian…
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Added:
7 months ago
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Radcliffe Cardiology
Results from the Phase III VICTOR trial, presented at the European Society of Cardiology (ESC) Congress 2025 and published in The Lancet, show that vericiguat did not meet its primary endpoint in patients with chronic, stable heart failure with reduced ejection fraction (HFrEF).¹˒²Vericiguat is an oral, once-daily stimulator of soluble guanylate cyclase (sGC), an enzyme in the nitric oxide…
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Added:
5 months ago
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Radcliffe Cardiology
A prespecified secondary analysis of the DAN-RSV trial has found that a bivalent respiratory syncytial virus (RSV) vaccine is similarly effective against respiratory and cardiovascular outcomes in older adults, regardless of pre-existing atherosclerotic cardiovascular disease (ASCVD).¹The bivalent RSV prefusion F protein-based (RSVpreF) vaccine contains stabilised prefusion F glycoproteins from…
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Added:
8 months ago
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Radcliffe CVRM
A secondary analysis of the SUMMIT trial has found that the benefits of tirzepatide on reducing the risk of cardiovascular death or worsening heart failure (HF) are consistent across all levels of obesity in patients with heart failure with preserved ejection fraction (HFpEF).¹ However, patients with a higher baseline body mass index (BMI) experienced greater improvements in exercise capacity and…
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Added:
7 months ago
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Radcliffe Cardiology
A prespecified secondary analysis of the DANFLU-2 trial suggests that a high-dose inactivated influenza vaccine (HD-IIV) may offer greater protection against cardiovascular-related hospitalisations in older adults compared to a standard-dose vaccine (SD-IIV).¹˒² While the trial’s primary endpoint was not met, these exploratory findings point to a potential benefit in reducing the burden of…
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Added:
1 year ago
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THT
THT conference has released its four late-breaking trial sessions for 2025.The fourth annual Technology and Heart Failure Therapeutics conference is set to take place from the 11th to 13th February at Omni Boston Hotel at the Seaport in Boston. Access the full programme here.Late Breaking Clinical Science Session ITuesday 11th February, 09:30 – 10:45am ESTRobotic Surgical Technique for Performing…
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Added:
8 months ago
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Radcliffe Cardiology
Transthyretin amyloid cardiomyopathy (ATTR-CM) is a progressive and fatal disease characterised by the deposition of amyloid fibrils in the heart. A new analysis from the HELIOS-B trial has found that key echocardiographic measures are strong predictors of clinical outcomes and that the RNA interference (RNAi) therapeutic vutrisiran attenuates the decline in cardiac function in this patient…
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Added:
8 months ago
Source:
Radcliffe Cardiology
With global temperatures rising and heatwaves becoming more frequent and intense, the impact on public health is a growing concern. A new scientific statement from the European Society of Cardiology (ESC) and several of its constituent bodies highlights the significant risk that extreme heat poses to cardiovascular health, particularly for the elderly and individuals with pre-existing…
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