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10 months ago
ESC Congress 2025 - Digitoxin reduced the risk of all-cause mortality and hospitalisation in patients with worsening heart failure.Dr Harriette Van Spall (McMaster University, CA) sits down with Prof Udo Bavendiek to explore the DIGIT-HF trial, investigating whether digitoxin can improve outcomes in patients with advanced chronic heart failure and reduced ejection fraction.This landmark study…
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2 months ago
HFA Congress 2026 — Dr Ida Arentz Taraldsen (Amager and Hvidovre Hospital, Copenhagen University Hospital, Hvidovre, DK) discusses REDOX-AHF, a prospective, randomised, blinded, multicentre pilot trial evaluating restrictive versus liberal oxygenation targets in patients hospitalised with acute heart failure and pulmonary congestion.Although oxygen therapy is widely used in the acute management…
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2 months ago
HFA Congress 2026 — Dr Nir Uriel (NewYork-Presbyterian, New York, US) discusses findings from a comparative analysis evaluating survival outcomes in middle-aged and older patients with advanced heart failure treated with left ventricular assist device (LVAD) therapy or heart transplantation.Drawing on two prospectively collected data sets: the Momentum 3 trial (HeartMate 3) and the UNOS…
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1 year ago
HFSA 24 - Dr Akshay Desai (Brigham and Women’s Hospital, US) sits down with us to discuss the findings from FINEARTS-HF across the ejection fraction spectrum in heart failure with mildly reduced and preserved ejection fraction.Interview Questions:1. What was the reasoning behind this study? What was the study design and patient population?2. What was the study design and patient population?3…
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1 year ago
THT Conference 2025 - Outcomes after heart failure patients were treated with an interatrial shunt show heart failure with reduced ejection fraction (HFrEF) patients had further benefit compared to heart failure with preserved ejection fraction (HFpEF) patients. The study's prediction model revealed four independent predictors of two-year adverse outcomes in HFrEF patients treated with medical…
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1 year ago
ESC HF 25 - A study investigating CRISPR gene editing with nexiguran ziclumeran in ATTR cardiomyopathy demonstrated favourable safety and tolerability, with consistent reductions in serum TTR in both wild-type and variant disease.Prof Marianna Fontana (University College London, UK) joins us to discuss the key findings from a two-part, open-label, phase 1 study investigating the treatment effect,…
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1 year ago
In this Meet the Experts session, from e-SPACE Heart Failure 2024, Prof Shelley Zieroth, Dr Shahzeb Khan and Prof Gianluigi Savarese examine the clinical impact of hyperkalemia in heart failure and discuss strategies for its long-term management.
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1 year ago
In this Meet the Experts session, from e-SPACE Heart Failure 2024, Prof Giuseppe Rosano and Dr Stephen Greene discuss the implementation of guideline-directed medical therapy (GDMT) in heart failure and strategies to overcome clinical inertia.
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1 year ago
THT Conference 2025 - Findings show catheter ablation of the right greater splanchnic nerve (GSN) in patients with heart failure with preserved ejection fraction (HFpEF) reduced estimated stressed blood volume in patients whether the ablation caused clinical benefits or not. This outcome indicates a confirmation of technical success that correlates with prior single-arm study findings.Dr Marat…
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2 years ago
HFA 24 - Late-breaker host, Dr Harriette Van Spall (McMaster University, CA) joined onsite by Dr Jasper Brugts (Erasmus University Medical Centre, NL) to discuss the first results from the TITRATE-HF study.TITRATE-HF is a real-world multicenter longitudinal study which aims to assess drug sequencing strategies for guideline-directed medical therapy (GDMT) initiation in patients with de novo,…
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